In men, with muscle wasting conditions, growth hormone therapy is often used to improve fat free mass. The study noted above demonstrates the alternatives to growth hormone therapy to achieve similar outcomes. DECA has both the characteristics of testosterone, but much greater activity towards stimulating muscle growth and improving recovery after strenuous resistance exercise. DECA is used clinically to treat patients with burns, radiation therapy, sarcopenia and muscle wasting conditions.
Deca has a long half and binds with a strong affinity to androgen receptors. Deca, unlike testosterone, does not undergo conversion to DHT and has less effect on hair follicles. Deca is often provided with testosterone to prevent suppression of the hypopituitary gonadal axis and maintain certain male physiologic processes.
Learn more. Deca Durabolin, also known as Nandrolone , is a world-famous anabolic steroid capable of increasing muscle mass in record time. This drug is still widely used in bodybuilding. Given the fact that anabolic steroids have long been banned in many countries around the world, legal steroids have appeared on the market of sports supplements, which are an excellent substitute for them.
Currently, the only and legal alternative to Deca Durabolin is the natural steroid — DecaDuro. It is absolutely legal and can be bought without legal consequences. Both drugs are aimed at accelerated muscle growth , so their effectiveness cannot be discussed. However, these drugs have some differences. Deca Durabolin is a synthetic product that is banned worldwide due to various side effects that are dangerous to health and even life-threatening.
DecaDuro is a legal steroid developed by CrazyBulk. It is absolutely safe and legal. The supplement consists of natural ingredients and is not capable of causing harm to health. Therefore, most athletes successfully use it. Deca Durabolin steroid is a Nandrolone 2 brand product and belongs to the class of anabolic androgens.
It was created in and is still popular among bodybuilding. Deca Durabolin steroid release form is an intramuscular or subcutaneous injection. It is worth noting that the drug was initially used for medical purposes to treat many diseases, for example, osteoporosis, anemia, and oncological diseases of the mammary glands. Later it became popular among athletes and many of them experienced its incredible effects.
With the help of this drug, athletes achieved accelerated muscle growth and an increase in strength indicators. Deca Durabolin results are really impressive. Therefore, despite its illegality and danger, many athletes seek to acquire it. Fortunately, today there is a legal alternative called DecaDuro. With it, you can achieve all the goals and it is in no way inferior to a synthetic rival. In my DecaDuro review , I examined the active effect of the drug and all its advantages.
Read it and study the drug in more detail, I think it will be interesting to you. Deca Durabolin steroids, like most other anabolic steroids, is famous for its negative health effects. Some of the side effects of the drug are irreversible. Congestive heart failure, myocardial rupture, and fat embolism can result. Prolonged use of deca steroids can cause syncope, palpitations, vasculitis, and thromboembolism. Steroid use can lead to acne and allergic dermatitis.
It can impair wound healing of the skin and also increase sweating and rash. It makes the skin thin and fragile and can cause the formation of erythema and petechiae, among other things. Steroids can decrease the tolerance to carbohydrates and glucose in the body and cause the development of a cushingoid state. It is common to have hyperglycemia due to the use of steroids, which leads to an increased requirement of insulin and oral hypoglycemic agents.
It can also cause menstrual irregularities and pituitary unresponsiveness in patients. Vulnerable patients can develop congestive heart failure due to steroids. The drugs can also cause fluid retention in the body.
Sodium retention and potassium loss are some other side effects of the prolonged use of decadron steroids. Some patients on steroid therapy are noted to develop abdominal distention. There is an increase in their serum enzyme levels. But this is usually reversible, and the levels soon return to the normal range once steroids are discontinued. Steroids can increase appetite and also cause nausea.
Risk of peptic ulcer and subsequent perforation increases with this drug. Loss of muscle mass and muscle weakness can result due to the use of steroids.
Therefore, deca steroids should never be confused with anabolic steroids used for bodybuilding. Decadron can cause pathologic fracture of long bone and tendon rupture. Depression, mood swings, and emotional instability are often associated with prolonged use of steroids. Patients also complain of headaches. Once the treatment is stopped, patients can develop insomnia, personality changes, and vertigo in the initial days.
Patients on steroid therapy are more likely to develop infections. During steroid use, the body has a decreased ability to develop resistance or localize infection. The infection can be mild or severe. Keep in mind that the rate of infectious complications is likely to increase with the increased dose of steroids. Furthermore, the signs of current infection can be masked due to the use of the steroid. Steroids can worsen systemic fungal infections in the body.
Therefore, unless there is some life-threatening indication, it is best to avoid deca steroids in patients with such infections. Cases have been reported wherein the use of steroids alongside antifungals has led to cardiac enlargement and congestive heart failure. Steroids can also cause activation of latent disease or exacerbate an already existing infection caused by pathogens like candida, Nocardia, toxoplasma, and Cryptococcus, among others.
This is why it is advisable to rule out latent or active amebiasis before starting decadron steroid in any patient. Steroids should be used with immense caution in patients who are suspected of having threadworm infestation. Decadron causes immunosuppression, which can worsen the septicemia in such patients. Indeed, it can even prove to be fatal. Similarly, steroids should never be used for the management of cerebral malaria. Steroids should be used only in patients of active tuberculosis if they have disseminated tuberculosis.
In this case, the steroid helps in the management of the condition. If the drug is indicated in latent tuberculosis, close observation is imperative. Prolonged therapy will require these patients to receive chemoprophylaxis to minimize the complications. The use of decadron steroids can increase intraocular pressure and cause glaucoma and posterior subcapsular cataracts.
If a patient is required to use steroids long-term, certain measures have to be taken to minimize the potentially fatal risks associated with it. Large doses of steroids can lead to increased blood pressure, along with sodium and water retention in the body.
It is critical to restrict salt in the diet and incorporate potassium supplementations during this period. J Drug Educ ; 34 Kicman AT. Pharmacology of anabolic steroids. Br J Pharmacol ; Urinary nandrolone metabolites of endogenous origin in man: a confirmation by output regulation under human chorionic gonadotropin stimulation. J Clin Endocrinol Metab ; 86 Different patterns of metabolism determine the relative anabolic activity of norandrogens. J Steroid Biochem Mol Biol ; 53 Synthesis and aromatization of norandrogens in the stallion testis.
J Steroid Biochem ; 32 Piraccini BM, Alessandrini A. Androgenetic alopecia. G Ital Dermatol Venereol ; Topical testosterone supplementation for the treatment of male hypogonadism. Drugs ; 72 The role of non-aromatizable testosterone metabolite in metabolic pathways. Physiol Res ; 60 Steroid 5alpha-reductase deficiency in man: an inherited form of male pseudohermaphroditism.
Science ; Finasteride in the treatment of men with androgenetic alopecia. J Am Acad Dermatol ; 39 Finasteride in the treatment of alopecia. Expert Opin Pharmacother ; 5 Pathways and genes involved in steroid hormone metabolism in male pigs: a review and update. J Steroid Biochem Mol Biol ; Houghton E. Studies related to the metabolism of anabolic steroids in the horse: nortestosterone.
Xenobiotica ; 7 Mysore V. Finasteride and sexual side effects. Indian Dermatol Online J ; 3 Persistent sexual, emotional, and cognitive impairment post-finasteride: a survey of men reporting symptoms.
Am J Mens Health ; 9 Irwig MS. Persistent sexual side effects of finasteride: could they be permanent? J Sex Med ; 9 Patients treated for male pattern hair with finasteride show, after discontinuation of the drug, altered levels of neuroactive steroids in cerebrospinal fluid and plasma. Anabolic steroids reduce muscle damage caused by rotator cuff tendon release in an experimental study in rabbits.
J Bone Joint Surg Am ; 93 The effect of local use of nandrolone decanoate on rotator cuff repair in rabbits. J Invest Surg ; 23 The effect of anabolic steroids on the biomechanical and histological properties of rat tendon.
J Bone Joint Surg Am ; 74 Wang VM. Important preliminary findings on the potential role for nandrolone decanoate in the treatment of chronic rotator cuff tears. J Bone Joint Surg Am ; 93 :e Nandrolone decanoate as anabolic therapy in chronic kidney disease: a randomized phase II dose-finding study. Nephron Clin Pract ; :c Impact of testosterone on body fat composition. J Cell Physiol ; Testosterone supplementation therapy in the treatment of patients with metabolic syndrome.
Postgrad Med ; Effects of testosterone supplementation on markers of the metabolic syndrome and inflammation in hypogonadal men with the metabolic syndrome: the double-blinded placebo-controlled Moscow study. Clin Endocrinol Oxf ; 73 A positive role for anabolic androgenic steroids: preventing metabolic syndrome and type 2 diabetes mellitus.
Fertil Steril ; :e5. Dihydrotestosterone is the active androgen in the maintenance of nitric oxide-mediated penile erection in the rat. Endocrinology ; The effects of androgen on penile reflex, erectile response to electrical stimulation and penile NOS activity in the rat. Asian J Androl ; 1 The effects of transdermal dihydrotestosterone in the aging male: a prospective, randomized, double blind study.
J Clin Endocrinol Metab ; 87 J Sex Med ; 5 Purkayastha S, Mahanta R.
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